Research in developmental biology has led to the discovery of several types of stem cells, including embryonic stem (ES) cells, embryonic germ cells, and adult stem cells. Techniques and reagents developed for the in vitro culture, manipulation and characterization of stem cells provide unprecedented opportunities to study embryology and develop disease treatments. R&D Systems offers the following kits and panels for stem cell research:
- Identification Kits
- Stem Cell Antibody Panels
- Stem Cell Antibody Arrays
- Lineage Depletion Antibodies & Kits
Identification Kits
Human MSC Functional Identification Kit (Catalog # SC006)
Mouse MSC Functional Identification Kit (Catalog # SC010)
Designed for in vitro identification of human bone marrow-derived stem cells (BMSC)/mesenchymal stem cells (MSC) based on their ability to differentiate into multiple mesenchymal lineages. The kit contains specially formulated media supplements and a panel of antibodies for the differentiation and identification of adipocytes, chondrocytes and osteocytes.
Human Mesenchymal Stem Cell Functional Identification Kit (Catalog # SC006)
Kit Contents
- Adipogenic Supplement
- Anti-Aggrecan
- Chondrogenic Supplement
- Anti-FABP4
- Osteogenic Supplement
- Anti-Osteocalcin
- ITS Supplement
Mouse Mesenchymal Stem Cell Functional Identification Kit (Catalog # SC010)
Kit Contents
Stem Cell Antibody Panels
Human Embryonic Stem Cell Marker Antibody Panel (Catalog # SC008)
These panels are designed for analyzing the differentiation status of human ES cells by evaluating ES cell marker expressions. Each panel contains a group of antibodies that are recognized as markers for undifferentiated human ES cells.
Kit ContentsHuman Embryonic Stem Cell Marker Antibody Panel Plus (Catalog # SC009)
- Anti-Alkaline
- Anti-SSEA-1
- Anti-Nanog
- Anti-SSEA-4
- Anti-Oct3/4
Kit Contents
Stem Cell Antibody Arrays
Proteome ProfilerTM Human Pluripotent Stem Cell Array (Catalog # ARY010)
The Proteome Profiler Human Pluripotent Stem Cell Antibody Array (Catalog # ARY010) can be used to detect the relative levels of expression of 15 different stem cell markers. No specialized equipment is necessary.
Analytes Detected
Lineage Depletion Antibodies and Kits
Lineage depletion antibodies and kits can be used to enrich for uncommitted cell populations
Mouse Lineage Depletion Panel
Consists of lineage marker antibodies optimized to sufficiently bind 1 x 109 bone marrow derived cells. This panel can conveniently be used in conjunction with magnetic particle separation systems or flow cytometric cell sorting to deplete lineage-committed cells for the enrichment of mouse uncommitted mesenchymal or hematopoietic stem cells.
Description Catalog # Anti-CD3 MAB4841 Anti-CD4 MAB554 Anti-CD5 MAB115 Anti-CD8 alpha MAB116 Anti-CD11b/Integrin alpha M MAB1124 Anti-Ly-6G/Gr-1 MAB1037 Anti-CD45R/B220 MAB1217 Anti-TER-119 MAB1125 Mouse Lineage Depletion Protocol
MagCellect™ Mouse Hematopoietic Cell Lineage Depletion Kit** (Catalog # MAGM209)
Is designed for the enrichment of hematopoietic non-lineage committed cells (lineage negative) from mouse bone marrow. Lineage committed cells (lineage positive) targeted for depletion include T cells, B cells, NK cells, monocytes/macrophages, granulocytes and erythrocytes. The resulting cell population is highly enriched for SCF R/c-kit/CD117+ cells to a purity of 40 to 70% (depending on mouse strain) with less than 5% residual lineage positive cells. This kit is for use with the MagCellect Magnet (Catalog # MAG997), sold separately.
Kit Contents
- Anti-CD5
- Anti-TER-119
- Anti-CD11b
- Streptavidin Ferrofluid
- Anti-CD45R/B220
- Blocking Reagent
- Anti-Ly-6G/Gr-1
- 10X Buffer
*Sold under license from StemCells California, Inc. U.S. Patent Nos. 5,750,376, 5,851,832, 5,980,885, 5,968,829, 5,981,165, 6,071,889, 6,093,531, 6,103,530, 6,165,783, 6,238,922.
**This product utilizes and/or contains technology licensed from Veridex, LLC, Raritan, New Jersey 08869, USA, which is covered by one or more claims of United States and International patents and/or pending patent applications.